AX-15836 (AX15836)是有效，选择性的ERK5抑制剂，IC50值为8 nM。 AX-15836是一种选择性的和可逆的ERK5抑制剂，IC50值为8 nM，ERK5的抑制具有抗炎和抗肿瘤作用。在200多种激酶中，AX-15836对ERK5的选择性大于1000倍。
参考文献
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