本品是由YSFluorTM 647标记的山羊抗兔IgG（H+L），使用抗原偶联的琼脂糖微珠从山羊抗血清内亲和色谱纯化所得。免疫电泳和/或ELISA法检测显示本品特异性结合完整的兔IgG分子，也会与其他兔免疫球蛋白的轻链结合。可能会与其他物种免疫球蛋白发生交叉反应，但不会识别非免疫球蛋白类的血清蛋白。
YSFluorTM 647，Amax（最大激发波长）为651nm，Emax（最大发射波长）为667nm, 同Alex Fluor 647和APC的光谱性质一样，通常可考虑相互替代。本品适合做单标实验。要做多标（multiple-labeling）实验，建议使用与相近物种血清蛋白或者免疫球蛋白预先经过亲和吸附处理的二抗。
-25 ~ -15℃分装保存，尽量避免反复冻融。
[1] Zhou Y, Ke P, Bao X, et al. Peptide nano-blanket impedes fibroblasts activation and subsequent formation of pre-metastatic niche. Nat Commun. 2022;13(1):2906. Published 2022 May 25. doi:10.1038/s41467-022-30634-8(IF:14.919)
[2] Jin ZR, Fang D, Liu BH, et al. Roles of CatSper channels in the pathogenesis of asthenozoospermia and the therapeutic effects of acupuncture-like treatment on asthenozoospermia. Theranostics. 2021;11(6):2822-2844. Published 2021 Jan 1. doi:10.7150/thno.51869(IF:11.556)
[3] Zhang B, Wang H, Liao Z, et al. EGFP-EGF1-conjugated nanoparticles for targeting both neovascular and glioma cells in therapy of brain glioma. Biomaterials. 2014;35(13):4133-4145. doi:10.1016/j.biomaterials.2014.01.071(IF:8.312)
[4] Luo Z, Jin K, Pang Q, et al. On-Demand Drug Release from Dual-Targeting Small Nanoparticles Triggered by High-Intensity Focused Ultrasound Enhanced Glioblastoma-Targeting Therapy. ACS Appl Mater Interfaces. 2017;9(37):31612-31625. doi:10.1021/acsami.7b10866(IF:7.504)
[5] Wang C, Zhang J, Song S, et al. Imaging epileptic foci in mouse models via a low-density lipoprotein receptor-related protein-1 targeting strategy. EBioMedicine. 2021;63:103156. doi:10.1016/j.ebiom.2020.103156(IF:5.736)
[6] Wang L, Qian Y, Che X, Jiang J, Suo J, Wang Z. Isolation and Characterization of Primary Retinal Microglia From the Human Post-mortem Eyes for Future Studies of Ocular Diseases. Front Cell Neurosci. 2022;15:786020. Published 2022 Jan 13. doi:10.3389/fncel.2021.786020(IF:5.505)
[7] Zhao J, Xie W, Yang Z, et al. Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles. FASEB J. 2022;36(6):e22366. doi:10.1096/fj.202101690RR(IF:5.192)
[8]Yan Z., Zhen L., Zhu Z., et al. Direct cytosolic delivery of siRNA via cell membrane fusion using cholesterol-enriched exosomes. Nature nanotechnology(2024). doi.org/10.1038/s41565-01785-024-01785-0
