Fibroblast growth factor 13 (FGF13), a member of the FGF11 subfamily, is a kind of intracrine protein similar to other family members including FGF11, FGF12, and FGF14. Unlike classical FGF, FGF13 exerts its bioactivities independent of fibroblast growth factor receptors (FGFRs). FGF13, a nonsecretory protein of the FGF family, is expressed in cerebral cortical neurons during development and is a candidate gene for syndromal and nonspecific forms of X-chromosome-linked mental retardation. The FGF-13 regulates glioma cell invasion and is important for bevacizumab-induced glioma invasion. FGF-13 plays a crucial role in neuron polarization and migration in the cerebral cortex. In mouse FGF-13 RNA was detected in developing central nervous system in cells, and was also found throughout the peripheral nervous system.
高纯度、高活性、低内毒素、高批间一致性
-25 ~ -15℃保存，收到货之后有效期1年。 复溶后，无菌条件下，2~8℃保存，7天有效期。复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。
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